2,3-Difluoro-4-isopropoxyphenylboronic acid
(2,3-Difluoro-4-isopropoxyphenyl)boronic acid
CAS: 1154762-01-2
Molecular Formula: C9H11BF2O3
2,3-Difluoro-4-isopropoxyphenylboronic acid - Names and Identifiers
2,3-Difluoro-4-isopropoxyphenylboronic acid - Physico-chemical Properties
| Molecular Formula | C9H11BF2O3 |
| Molar Mass | 215.99 |
| Density | 1.25±0.1 g/cm3(Predicted) |
| Boling Point | 321.1±52.0 °C(Predicted) |
| pKa | 7.49±0.58(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | IRRITANT |
| MDL | MFCD19237183 |
2,3-Difluoro-4-isopropoxyphenylboronic acid - Introduction
boronic acid is an organic compound with the chemical formula C10H12BF2O3.
Its properties are as follows:
Appearance: Colorless crystalline solid
Melting point: about 153-155 degrees Celsius
Solubility: Soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane (DCM), not easily soluble in water.
(2,) The use of boronic acid is mainly concentrated in the field of organic synthesis. It is an important aryl boronic acid that can be used as a ligand to participate in metal-catalyzed reactions, especially in Suzuki-Miyaura coupling reactions, it can react with halogenated aromatic hydrocarbons to form C- C bonds. The compound can also be used as a precursor of fluorescent dyes for bioimaging and fluorescent labeling.
regarding the preparation method,(2,) boronic acid can be synthesized by various methods. the common method is to react (2,3-Difluoro-4-bmophenyl) boronic with isopropoxylated reagent. Specific synthetic methods can be found in the synthetic handbook of organic chemistry or related literature.
Regarding safety information, pay attention to safe operation when using chemicals. (2) boronic acid has not been reported to cause serious harm to human health and the environment. However, any chemical should be used with caution, avoiding direct contact with the skin and eyes, and avoiding inhaling its dust or vapor. Wear appropriate protective safety equipment such as laboratory gloves and goggles during use. If there is an accident, should immediately take appropriate first aid measures, and consult a professional doctor's opinion.
Its properties are as follows:
Appearance: Colorless crystalline solid
Melting point: about 153-155 degrees Celsius
Solubility: Soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane (DCM), not easily soluble in water.
(2,) The use of boronic acid is mainly concentrated in the field of organic synthesis. It is an important aryl boronic acid that can be used as a ligand to participate in metal-catalyzed reactions, especially in Suzuki-Miyaura coupling reactions, it can react with halogenated aromatic hydrocarbons to form C- C bonds. The compound can also be used as a precursor of fluorescent dyes for bioimaging and fluorescent labeling.
regarding the preparation method,(2,) boronic acid can be synthesized by various methods. the common method is to react (2,3-Difluoro-4-bmophenyl) boronic with isopropoxylated reagent. Specific synthetic methods can be found in the synthetic handbook of organic chemistry or related literature.
Regarding safety information, pay attention to safe operation when using chemicals. (2) boronic acid has not been reported to cause serious harm to human health and the environment. However, any chemical should be used with caution, avoiding direct contact with the skin and eyes, and avoiding inhaling its dust or vapor. Wear appropriate protective safety equipment such as laboratory gloves and goggles during use. If there is an accident, should immediately take appropriate first aid measures, and consult a professional doctor's opinion.
Last Update：2024-04-10 22:29:15
